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Bicarbonate-responsive “soluble” adenylyl cyclase defines a nuclear cAMP microdomain
Bicarbonate-responsive “soluble” adenylyl cyclase resides, in part, inside the mammalian cell nucleus where it stimulates the activity of nuclear protein kinase A to phosphorylate the cAMP response element binding protein (CREB). The existence of this complete and functional, nuclear-localized cAMP...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172001/ https://ncbi.nlm.nih.gov/pubmed/14769862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311119 |
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