Raf-1 regulates Rho signaling and cell migration

Raf kinases relay signals inducing proliferation, differentiation, and survival. The Raf-1 isoform has been extensively studied as the upstream kinase linking Ras activation to the MEK/ERK module. Recently, however, genetic experiments have shown that Raf-1 plays an essential role in counteracting a...

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Bibliografiske detaljer
Main Authors: Ehrenreiter, Karin, Piazzolla, Daniela, Velamoor, Vanishree, Sobczak, Izabela, Small, J. Victor, Takeda, Junji, Leung, Thomas, Baccarini, Manuela
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171799/
https://ncbi.nlm.nih.gov/pubmed/15753127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409162
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