RKIP Regulates MAP Kinase Signaling in Cells with Defective B-Raf Activity

MAP kinase (MAPK) signaling results from activation of Raf kinases in response to external or internal stimuli. Here, we demonstrate that Raf Kinase Inhibitory Protein (RKIP) regulates the activation of MAPK when B-Raf signaling is defective. We used multiple models including mouse embryonic fibrobl...

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Detalhes bibliográficos
Main Authors: Zeng, Lingchun, Ehrenreiter, Karin, Menon, Jyotsana, Menard, Ray, Kern, Florian, Nakazawa, Yoko, Bevilacqua, Elena, Imamoto, Akira, Baccarini, Manuela, Rosner, Marsha Rich
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622756/
https://ncbi.nlm.nih.gov/pubmed/23416466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.02.005
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