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RKIP Regulates MAP Kinase Signaling in Cells with Defective B-Raf Activity

MAP kinase (MAPK) signaling results from activation of Raf kinases in response to external or internal stimuli. Here, we demonstrate that Raf Kinase Inhibitory Protein (RKIP) regulates the activation of MAPK when B-Raf signaling is defective. We used multiple models including mouse embryonic fibrobl...

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Bibliografiska uppgifter
Huvudupphovsmän: Zeng, Lingchun, Ehrenreiter, Karin, Menon, Jyotsana, Menard, Ray, Kern, Florian, Nakazawa, Yoko, Bevilacqua, Elena, Imamoto, Akira, Baccarini, Manuela, Rosner, Marsha Rich
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622756/
https://ncbi.nlm.nih.gov/pubmed/23416466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.02.005
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