Raf Kinase Inhibitory Protein Protects Cells against Locostatin-Mediated Inhibition of Migration

BACKGROUND: Raf Kinase Inhibitory Protein (RKIP, also PEBP1), a member of the Phosphatidylethanolamine Binding Protein family, negatively regulates growth factor signaling by the Raf/MAP kinase pathway. Since an organic compound, locostatin, was reported to bind RKIP and inhibit cell migration by a...

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Autori principali: Shemon, Anne N., Eves, Eva M., Clark, Matthew C., Heil, Gary, Granovsky, Alexey, Zeng, Lingchun, Imamoto, Akira, Koide, Shohei, Rosner, Marsha Rich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696091/
https://ncbi.nlm.nih.gov/pubmed/19551145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006028
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