Catalytically inactive human cathepsin D triggers fibroblast invasive growth

The aspartyl-protease cathepsin D (cath-D) is overexpressed and hypersecreted by epithelial breast cancer cells and stimulates their proliferation. As tumor epithelial–fibroblast cell interactions are important events in cancer progression, we investigated whether cath-D overexpression affects also...

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Autores principales: Laurent-Matha, Valérie, Maruani-Herrmann, Sharon, Prébois, Christine, Beaujouin, Mélanie, Glondu, Murielle, Noël, Agnès, Alvarez-Gonzalez, Marie Luz, Blacher, Sylvia, Coopman, Peter, Baghdiguian, Stephen, Gilles, Christine, Loncarek, Jadranka, Freiss, Gilles, Vignon, Françoise, Liaudet-Coopman, Emmanuelle
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171724/
https://ncbi.nlm.nih.gov/pubmed/15668295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403078
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