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Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B
The current mechanism proposed for the processing and activation of the 52 kDa lysosomal aspartic protease cathepsin D (cath-D) is a combination of partial auto-activation generating a 51 kDa pseudo-cath-D, followed by enzyme-assisted maturation involving cysteine and/or aspartic proteases and yield...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Published by Oxford University Press for Japanese Biochemical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376303/ https://ncbi.nlm.nih.gov/pubmed/16567401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvj037 |
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