Llwytho...

Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity

The aspartic protease cathepsin D (cath-D) is a key mediator of induced-apoptosis and its proteolytic activity has been generally involved in this event. During apoptosis, cath-D is translocated to the cytosol. Since cath-D is one of the lysosomal enzymes which requires a more acidic pH to be proteo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beaujouin, Mélanie, Baghdiguian, Stephen, Glondu-Lassis, Murielle, Berchem, Guy, Liaudet-Coopman, Emmanuelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246153/
https://ncbi.nlm.nih.gov/pubmed/16331270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209221
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