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The Rho kinases I and II regulate different aspects of myosin II activity
The homologous mammalian rho kinases (ROCK I and II) are assumed to be functionally redundant, based largely on kinase construct overexpression. As downstream effectors of Rho GTPases, their major substrates are myosin light chain and myosin phosphatase. Both kinases are implicated in microfilament...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171463/ https://ncbi.nlm.nih.gov/pubmed/16043513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412043 |
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