The Rho kinases I and II regulate different aspects of myosin II activity

The homologous mammalian rho kinases (ROCK I and II) are assumed to be functionally redundant, based largely on kinase construct overexpression. As downstream effectors of Rho GTPases, their major substrates are myosin light chain and myosin phosphatase. Both kinases are implicated in microfilament...

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Bibliographic Details
Main Authors: Yoneda, Atsuko, Multhaupt, Hinke A.B., Couchman, John R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171463/
https://ncbi.nlm.nih.gov/pubmed/16043513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412043
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