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Phosphorylation and mRNA Splicing of Collapsin Response Mediator Protein-2 Determine Inhibition of Rho-associated Protein Kinase (ROCK) II Function in Carcinoma Cell Migration and Invasion

The Rho-associated protein kinases (ROCK I and II) are central regulators of important cellular processes such as migration and invasion downstream of the GTP-Rho. Recently, we reported collapsin response mediator protein (CRMP)-2 as an endogenous ROCK II inhibitor. To reveal how the CRMP-2-ROCK II...

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Detalhes bibliográficos
Main Authors: Morgan-Fisher, Marie, Couchman, John R., Yoneda, Atsuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829433/
https://ncbi.nlm.nih.gov/pubmed/24036111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505602
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