Keratin 8 overexpression promotes mouse Mallory body formation

Keratins 8 and 18 (K8/18) are major constituents of Mallory bodies (MBs), which are hepatocyte cytoplasmic inclusions seen in several liver diseases. K18-null but not K8-null or heterozygous mice form MBs, which indicates that K8 is important for MB formation. Early stages in MB genesis include K8/1...

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Hauptverfasser: Nakamichi, Ikuo, Toivola, Diana M., Strnad, Pavel, Michie, Sara A., Oshima, Robert G., Baribault, Hélène, Omary, M. Bishr
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171301/
https://ncbi.nlm.nih.gov/pubmed/16365160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200507093
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