Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks

Protrusion of the leading edge of migrating epithelial cells requires precise regulation of two actin filament (F-actin) networks, the lamellipodium and lamella. Cofilin is a downstream target of Rho-GTPase signaling that promotes F-actin cycling through its F-actin nucleating, severing and depolyme...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Delorme, Violaine, Machacek, Matthias, DerMardirossian, Celine, Anderson, Karen L., Wittmann, Torsten, Hanein, Dorit, Waterman-Storer, Clare, Danuser, Gaudenz, Bokoch, Gary M.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170459/
https://ncbi.nlm.nih.gov/pubmed/17981134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.08.011
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares