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Compound C inhibits hypoxic activation of HIF-1 independent of AMPK

The key transcription factor that regulates the cellular responses to hypoxia is hypoxia inducible factor-1 (HIF-1). The signaling mechanisms that regulate the hypoxic activation of HIF-1 are not fully understood. Our objective here was to test whether AMP-activated kinase (AMPK) was an upstream reg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Emerling, Brooke M., Viollet, Benoit, Tormos, Kathryn V., Chandel, Navdeep S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169511/
https://ncbi.nlm.nih.gov/pubmed/18036344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.038
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