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Compound C inhibits hypoxic activation of HIF-1 independent of AMPK
The key transcription factor that regulates the cellular responses to hypoxia is hypoxia inducible factor-1 (HIF-1). The signaling mechanisms that regulate the hypoxic activation of HIF-1 are not fully understood. Our objective here was to test whether AMP-activated kinase (AMPK) was an upstream reg...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169511/ https://ncbi.nlm.nih.gov/pubmed/18036344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.038 |
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