Cd38/Adp-Ribosyl Cyclase: A New Role in the Regulation of Osteoclastic Bone Resorption

The multifunctional ADP-ribosyl cyclase, CD38, catalyzes the cyclization of NAD(+) to cyclic ADP-ribose (cADPr). The latter gates Ca(2+) release through microsomal membrane-resident ryanodine receptors (RyRs). We first cloned and sequenced full-length CD38 cDNA from a rabbit osteoclast cDNA library....

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Hauptverfasser: Sun, Li, Adebanjo, Olugbenga A., Moonga, Baljit S., Corisdeo, Susanne, Anandatheerthavarada, Hindupur K., Biswas, Gopa, Arakawa, Toshiya, Hakeda, Yoshiyuki, Koval, Antoliy, Sodam, Bali, Bevis, Peter J.R., Moser, A. James, Lai, F. Anthony, Epstein, Solomon, Troen, Bruce R., Kumegawa, Masayoshi, Zaidi, Mone
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169484/
https://ncbi.nlm.nih.gov/pubmed/10477767
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