Dexamethasone inhibits bone resorption by indirectly inducing apoptosis of the bone-resorbing osteoclasts via the action of osteoblastic cells

Although glucocorticoids (GCs) are physiologically essentialfor bone metabolism, it is generally accepted that high dosesof GCs cause bone loss through a combination of decreased boneformation and increased bone resorption. However, the actionof GCs on mature osteoclasts remains contradictory. In th...

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Bibliographic Details
Main Authors: Warabi, Shintaro, Tachibana, Yomei, Kumegawa, Masayoshi, Hakeda, Yoshiyuki
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers 2001
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466617/
https://ncbi.nlm.nih.gov/pubmed/19003278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008159332152
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