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Mode of Action of Interleukin-6 on Mature Osteoclasts. Novel Interactions with Extracellular Ca(2+) Sensing in the Regulation of Osteoclastic Bone Resorption
We describe a physiologically significant mechanism through which interleukin-6 (IL-6) and a rising ambient Ca(2+) interact to regulate osteoclastic bone resorption. VOXEL-based confocal microscopy of nonpermeabilized osteoclasts incubated with anti– IL-6 receptor antibodies revealed intense, strict...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149353/ https://ncbi.nlm.nih.gov/pubmed/9732294 |
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