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Cytochrome C Maintains Mitochondrial Transmembrane Potential and Atp Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

During apoptosis, cytochrome c is released into the cytosol as the outer membrane of mitochondria becomes permeable, and this acts to trigger caspase activation. The consequences of this release for mitochondrial metabolism are unclear. Using single-cell analysis, we found that when caspase activity...

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Autori principali: Waterhouse, Nigel J., Goldstein, Joshua C., von Ahsen, Oliver, Schuler, Martin, Newmeyer, Donald D., Green, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169468/
https://ncbi.nlm.nih.gov/pubmed/11309413
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