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The Rap GTPase Activator Drosophila PDZ-GEF Regulates Cell Shape in Epithelial Migration and Morphogenesis

Epithelial morphogenesis is characterized by an exquisite control of cell shape and position. Progression through dorsal closure in Drosophila gastrulation depends on the ability of Rap1 GTPase to signal through the adherens junctional multidomain protein Canoe. Here, we provide genetic evidence tha...

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Autori principali: Boettner, Benjamin, Van Aelst, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169160/
https://ncbi.nlm.nih.gov/pubmed/17846121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01275-07
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