The PDZ-GEF Gef26 regulates synapse development and function via FasII and Rap1 at the Drosophila neuromuscular junction

Guanine nucleotide exchange factors (GEFs) are essential for small G proteins to activate their downstream signaling pathways, which are involved in morphogenesis, cell adhesion, and migration. Mutants of Gef26, a PDZ-GEF (PDZ domain-containing guanine nucleotide exchange factor) in Drosophila, exhi...

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Publicat a:Exp Cell Res
Autors principals: Ou, Mengzhu, Wang, Su, Sun, Mingkuan, An, Jinsong, Lv, Huihui, Zeng, Xiankun, Hou, Steven X., Xie, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189168/
https://ncbi.nlm.nih.gov/pubmed/30553967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2018.12.008
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