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The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin

The AF-6 protein is a multidomain protein that contains two potential Ras-binding domains within its N terminus. Because of this feature, AF-6 has been isolated in both two-hybrid and biochemical approaches and is postulated to be a potential Ras-effector protein. Herein, we show that it is specific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boettner, Benjamin, Govek, Eve-Ellen, Cross, Justin, Van Aelst, Linda
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16822/
https://ncbi.nlm.nih.gov/pubmed/10922060
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