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The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo.

Rap1 belongs to the highly conserved Ras subfamily of small GTPases. In Drosophila, Rap1 plays a critical role in many different morphogenetic processes, but the molecular mechanisms executing its function are unknown. Here, we demonstrate that Canoe (Cno), the Drosophila homolog of mammalian juncti...

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Detalhes bibliográficos
Main Authors: Boettner, Benjamin, Harjes, Phoebe, Ishimaru, Satoshi, Heke, Michael, Fan, Hong Qing, Qin, Yi, Van Aelst, Linda, Gaul, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462758/
https://ncbi.nlm.nih.gov/pubmed/14504224
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