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A Recombinant Herpes Simplex Virus Type 1 Expressing Two Additional Copies of gK Is More Pathogenic than Wild-Type Virus in Two Different Strains of Mice

The effect of glycoprotein K (gK) overexpression on herpes simplex virus type 1 (HSV-1) infection in two different strains of mice was evaluated using a recombinant HSV-1 virus that expresses two additional copies of the gK gene in place of the latency-associated transcript (LAT). This mutant virus...

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מידע ביבליוגרפי
Main Authors: Mott, Kevin R., Perng, Guey-Chuen, Osorio, Yanira, Kousoulas, Konstantin G., Ghiasi, Homayon
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169076/
https://ncbi.nlm.nih.gov/pubmed/17898051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01442-07
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