Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B

Obesity and type 2 diabetes are characterized by insulin resistance. Mice lacking the protein-tyrosine phosphatase PTP1B in all tissues are hypersensitive to insulin but also have diminished fat stores. Because adiposity affects insulin sensitivity, the extent to which PTP1B directly regulates gluco...

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Huvudupphovsmän: Delibegovic, Mirela, Bence, Kendra K., Mody, Nimesh, Hong, Eun-Gyoung, Ko, Hwi Jin, Kim, Jason K., Kahn, Barbara B., Neel, Benjamin G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2007
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169063/
https://ncbi.nlm.nih.gov/pubmed/17724080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00959-07
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