Liver-Specific Deletion of Protein Tyrosine Phosphatase (PTP) 1B Improves Obesity- and Pharmacologically-Induced Endoplasmic Reticulum Stress

Obesity is associated with induction of endoplasmic reticulum (ER)-stress response signalling and insulin resistance. Protein tyrosine phosphatase (PTP)-1B is a major regulator of adiposity and insulin sensitivity. The aim of this study was to investigate the role of liver-PTP1B in chronically- (hig...

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Hlavní autoři: Agouni, Abdelali, Mody, Nimesh, Owen, Carl, Czopek, Alicja, Zimmer, Derek, Bentires-Alj, Mohamed, Bence, Kendra K., Delibegović, Mirela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744093/
https://ncbi.nlm.nih.gov/pubmed/21605081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110373
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