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TOR Signaling Is a Determinant of Cell Survival in Response to DNA Damage

The conserved TOR (target of rapamycin) kinase is part of a TORC1 complex that regulates cellular responses to environmental stress, such as amino acid starvation and hypoxia. Dysregulation of Akt-TOR signaling has also been linked to the genesis of cancer, and thus, this pathway presents potential...

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Detalhes bibliográficos
Main Authors: Shen, Changxian, Lancaster, Cynthia S., Shi, Bin, Guo, Hong, Thimmaiah, Padma, Bjornsti, Mary-Ann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168917/
https://ncbi.nlm.nih.gov/pubmed/17698581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00290-07
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