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TOR Signaling Is a Determinant of Cell Survival in Response to DNA Damage
The conserved TOR (target of rapamycin) kinase is part of a TORC1 complex that regulates cellular responses to environmental stress, such as amino acid starvation and hypoxia. Dysregulation of Akt-TOR signaling has also been linked to the genesis of cancer, and thus, this pathway presents potential...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2168917/ https://ncbi.nlm.nih.gov/pubmed/17698581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00290-07 |
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