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The Transcription-Dependent Dissociation of P-TEFb-HEXIM1-7SK RNA Relies upon Formation of hnRNP-7SK RNA Complexes

The positive transcription elongation factor P-TEFb controls the elongation of transcription by RNA polymerase II. P-TEFb is inactivated upon binding to HEXIM1 or HEXIM2 proteins associated with a noncoding RNA, 7SK. In response to the inhibition of transcription, 7SK RNA, as well as HEXIM proteins,...

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Main Authors: Barrandon, Charlotte, Bonnet, François, Nguyen, Van Trung, Labas, Valérie, Bensaude, Olivier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168891/
https://ncbi.nlm.nih.gov/pubmed/17709395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00975-07
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