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hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Disturbed RNA processing and subcellular transport contribute to the pathomechanisms of motoneuron diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. RNA-binding proteins are involved in these processes, but the mechanisms by which they regulate the subcellular diversity of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Briese, Michael, Saal-Bauernschubert, Lena, Ji, Changhe, Moradi, Mehri, Ghanawi, Hanaa, Uhl, Michael, Appenzeller, Silke, Backofen, Rolf, Sendtner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866599/
https://ncbi.nlm.nih.gov/pubmed/29507242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721670115
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