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Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons

Spinal muscular atrophy (SMA) is caused by deficiency of the ubiquitously expressed survival motoneuron (SMN) protein. SMN is crucial component of a complex for the assembly of spliceosomal small nuclear ribonucleoprotein (snRNP) particles. Other cellular functions of SMN are less characterized so f...

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Detalhes bibliográficos
Main Authors: Dombert, Benjamin, Sivadasan, Rajeeve, Simon, Christian M., Jablonka, Sibylle, Sendtner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206449/
https://ncbi.nlm.nih.gov/pubmed/25338097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110846
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