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Human Papillomavirus Type 16 E7 Oncoprotein Associates with the Centrosomal Component γ-Tubulin

Expression of a high-risk human papillomavirus (HPV) E7 oncoprotein is sufficient to induce aberrant centrosome duplication in primary human cells. The resulting centrosome-associated mitotic abnormalities have been linked to the development of aneuploidy. HPV type 16 (HPV16) E7 induces supernumerar...

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Detalhes bibliográficos
Main Authors: Nguyen, Christine L., Eichwald, Catherine, Nibert, Max L., Münger, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168839/
https://ncbi.nlm.nih.gov/pubmed/17913829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01669-07
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