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Mapping Protease Inhibitor Resistance to Human Immunodeficiency Virus Type 1 Sequence Polymorphisms within Patients

Resistance genotyping provides an important resource for the clinical management of patients infected with human immunodeficiency virus type 1 (HIV-1). However, resistance to protease (PR) inhibitors (PIs) is a complex phenotype shaped by interactions among nearly half of the residues in HIV-1 PR. P...

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Autori principali: Poon, Art F. Y., Kosakovsky Pond, Sergei L., Richman, Douglas D., Frost, Simon D. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168824/
https://ncbi.nlm.nih.gov/pubmed/17913806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01570-07
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