Phenotypic Hypersusceptibility to Multiple Protease Inhibitors and Low Replicative Capacity in Patients Who Are Chronically Infected with Human Immunodeficiency Virus Type 1

Increased susceptibility to the protease inhibitors saquinavir and amprenavir has been observed in human immunodeficiency virus type 1 (HIV-1) with specific mutations in protease (V82T and N88S). Increased susceptibility to ritonavir has also been described in some viruses from antiretroviral agent-...

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Detalhes bibliográficos
Main Authors: Martinez-Picado, Javier, Wrin, Terri, Frost, Simon D. W., Clotet, Bonaventura, Ruiz, Lidia, Brown, Andrew J. Leigh, Petropoulos, Christos J., Parkin, Neil T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091704/
https://ncbi.nlm.nih.gov/pubmed/15857976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.5907-5913.2005
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