Genotypic Changes in Human Immunodeficiency Virus Type 1 Protease Associated with Reduced Susceptibility and Virologic Response to the Protease Inhibitor Tipranavir

Tipranavir is a novel, nonpeptidic protease inhibitor of human immunodeficiency virus type 1 (HIV-1) with activity against clinical HIV-1 isolates from treatment-experienced patients. HIV-1 genotypic and phenotypic data from phase II and III clinical trials of tipranavir with protease inhibitor-expe...

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Bibliografiska uppgifter
Huvudupphovsmän: Baxter, John D., Schapiro, Jonathan M., Boucher, Charles A. B., Kohlbrenner, Veronika M., Hall, David B., Scherer, Joseph R., Mayers, Douglas L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641746/
https://ncbi.nlm.nih.gov/pubmed/16928764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00712-06
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