Tipranavir (TPV) Genotypic Inhibitory Quotient Predicts Virological Response at 48 Weeks to TPV-Based Salvage Regimens

The virological response (VR) to a tipranavir-ritonavir (TPV-RTV)-based regimen had been shown to be associated with a number of mutations in the protease gene, the use of enfuvirtide (T20), and the TPV phenotypic inhibitory quotient (IQ). The role of the TPV genotypic IQ (gIQ) has not yet been full...

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Библиографические подробности
Главные авторы: de Requena, Daniel Gonzalez, Bonora, Stefano, Calcagno, Andrea, D'Avolio, Antonio, Siccardi, Marco, Fontana, Silvia, Milia, Maria Grazia, Sciandra, Mauro, Garazzino, Silvia, Di Garbo, Antonio, Baietto, Lorena, Trentini, Laura, Di Perri, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
Предметы:
Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258544/
https://ncbi.nlm.nih.gov/pubmed/18160524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-07
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