Tipranavir (TPV) Genotypic Inhibitory Quotient Predicts Virological Response at 48 Weeks to TPV-Based Salvage Regimens

The virological response (VR) to a tipranavir-ritonavir (TPV-RTV)-based regimen had been shown to be associated with a number of mutations in the protease gene, the use of enfuvirtide (T20), and the TPV phenotypic inhibitory quotient (IQ). The role of the TPV genotypic IQ (gIQ) has not yet been full...

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Detalhes bibliográficos
Main Authors: de Requena, Daniel Gonzalez, Bonora, Stefano, Calcagno, Andrea, D'Avolio, Antonio, Siccardi, Marco, Fontana, Silvia, Milia, Maria Grazia, Sciandra, Mauro, Garazzino, Silvia, Di Garbo, Antonio, Baietto, Lorena, Trentini, Laura, Di Perri, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258544/
https://ncbi.nlm.nih.gov/pubmed/18160524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-07
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