Tipranavir (TPV) Genotypic Inhibitory Quotient Predicts Virological Response at 48 Weeks to TPV-Based Salvage Regimens

The virological response (VR) to a tipranavir-ritonavir (TPV-RTV)-based regimen had been shown to be associated with a number of mutations in the protease gene, the use of enfuvirtide (T20), and the TPV phenotypic inhibitory quotient (IQ). The role of the TPV genotypic IQ (gIQ) has not yet been full...

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Bibliografski detalji
Glavni autori: de Requena, Daniel Gonzalez, Bonora, Stefano, Calcagno, Andrea, D'Avolio, Antonio, Siccardi, Marco, Fontana, Silvia, Milia, Maria Grazia, Sciandra, Mauro, Garazzino, Silvia, Di Garbo, Antonio, Baietto, Lorena, Trentini, Laura, Di Perri, Giovanni
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258544/
https://ncbi.nlm.nih.gov/pubmed/18160524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-07
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