Development, Validation, and Routine Application of a High-Performance Liquid Chromatography Method Coupled with a Single Mass Detector for Quantification of Itraconazole, Voriconazole, and Posaconazole in Human Plasma

We have developed and validated a high-performance liquid chromatography method coupled with a mass detector to quantify itraconazole, voriconazole, and posaconazole using quinoxaline as the internal standard. The method involves protein precipitation with acetonitrile. Mean accuracy (percent deviat...

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Detalhes bibliográficos
Main Authors: Baietto, Lorena, D'Avolio, Antonio, Ventimiglia, Giusi, De Rosa, Francesco Giuseppe, Siccardi, Marco, Simiele, Marco, Sciandra, Mauro, Di Perri, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Analytical Procedures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916319/
https://ncbi.nlm.nih.gov/pubmed/20530230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01807-09
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