Multiplex Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Quantification in Human Plasma of Fluconazole, Itraconazole, Hydroxyitraconazole, Posaconazole, Voriconazole, Voriconazole-N-Oxide, Anidulafungin, and Caspofungin

Therapeutic drug monitoring (TDM) may contribute to optimizing the efficacy and safety of antifungal therapy because of the large variability in drug pharmacokinetics. Rapid, sensitive, and selective laboratory methods are needed for efficient TDM. Quantification of several antifungals in a single a...

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Detalhes bibliográficos
Main Authors: Decosterd, Laurent Arthur, Rochat, Bertrand, Pesse, Benoît, Mercier, Thomas, Tissot, Frédéric, Widmer, Nicolas, Bille, Jacques, Calandra, Thierry, Zanolari, Boris, Marchetti, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Analytical Procedures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981284/
https://ncbi.nlm.nih.gov/pubmed/20855739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00404-10
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