Hybrid Cell Vaccination Resolves Leishmania donovani Infection by Eliciting a Strong CD8(+) Cytotoxic T-Lymphocyte Response with Concomitant Suppression of Interleukin-10 (IL-10) but Not IL-4 or IL-13

There is an acute dearth of therapeutic interventions against visceral leishmaniasis that is required to restore an established defective cell-mediated immune response. Hence, formulation of effective immunotherapy requires the use of dominant antigen(s) targeted to elicit a specific antiparasitic c...

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Bibliographic Details
Main Authors:	Basu, Rajatava, Bhaumik, Suniti, Haldar, Arun Kumar, Naskar, Kshudiram, De, Tripti, Dana, Syamal Kumar, Walden, Peter, Roy, Syamal
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2007
Subjects:	Fungal and Parasitic Infections
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2168357/ https://ncbi.nlm.nih.gov/pubmed/17908806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00944-07
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Hybrid Cell Vaccination Resolves Leishmania donovani Infection by Eliciting a Strong CD8(+) Cytotoxic T-Lymphocyte Response with Concomitant Suppression of Interleukin-10 (IL-10) but Not IL-4 or IL-13

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