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Hybrid Cell Vaccination Resolves Leishmania donovani Infection by Eliciting a Strong CD8(+) Cytotoxic T-Lymphocyte Response with Concomitant Suppression of Interleukin-10 (IL-10) but Not IL-4 or IL-13
There is an acute dearth of therapeutic interventions against visceral leishmaniasis that is required to restore an established defective cell-mediated immune response. Hence, formulation of effective immunotherapy requires the use of dominant antigen(s) targeted to elicit a specific antiparasitic c...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2168357/ https://ncbi.nlm.nih.gov/pubmed/17908806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00944-07 |
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