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Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection

Nonsteroidal anti-inflammatory drugs (NSAIDs) are well-known cancer preventives, which have been largely attributed to their antiproliferative and apoptosis-inducing activities. In this study, we show that microsatellite instability (MSI) in colorectal cancer cells deficient for a subset of the huma...

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Autors principals: Rüschoff, Josef, Wallinger, Sabine, Dietmaier, Wolfgang, Bocker, Tina, Brockhoff, Gero, Hofstädter, Ferdinand, Fishel, Richard
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21637/
https://ncbi.nlm.nih.gov/pubmed/9736731
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