MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC)

Genomic instability at simple repeated sequences, termed microsatellite instability (MSI), plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC) more than 90% of cases show MSI, whereas only 10–15% of sporadic...

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Detalhes bibliográficos
Main Authors: Müller, Annegret, Edmonston, Tina Bocker, Dietmaier, Wolfgang, Büttner, Reinhard, Fishel, Richard, Rüschoff, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839272/
https://ncbi.nlm.nih.gov/pubmed/15528788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/343976
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