Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection

Nonsteroidal anti-inflammatory drugs (NSAIDs) are well-known cancer preventives, which have been largely attributed to their antiproliferative and apoptosis-inducing activities. In this study, we show that microsatellite instability (MSI) in colorectal cancer cells deficient for a subset of the huma...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Rüschoff, Josef, Wallinger, Sabine, Dietmaier, Wolfgang, Bocker, Tina, Brockhoff, Gero, Hofstädter, Ferdinand, Fishel, Richard
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11301
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