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Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection

Nonsteroidal anti-inflammatory drugs (NSAIDs) are well-known cancer preventives, which have been largely attributed to their antiproliferative and apoptosis-inducing activities. In this study, we show that microsatellite instability (MSI) in colorectal cancer cells deficient for a subset of the huma...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Rüschoff, Josef, Wallinger, Sabine, Dietmaier, Wolfgang, Bocker, Tina, Brockhoff, Gero, Hofstädter, Ferdinand, Fishel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11301
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