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Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection

Eukaryotic initiation factor (eIF) 4GI is a component of the cap-binding protein complex eIF4F, which is required for cap-dependent translation. Infection of cells by poliovirus results in a precipitous decline of host cell protein synthesis, which is preceded by the cleavage of eIF4GI. Cleavage of...

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Hlavní autoři: Gradi, Alessandra, Svitkin, Yuri V., Imataka, Hiroaki, Sonenberg, Nahum
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC21600/
https://ncbi.nlm.nih.gov/pubmed/9736694
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