Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap

Eukaryotic mRNAs possess a 5′-terminal cap structure (cap), m(7)GpppN, which facilitates ribosome binding. The cap is bound by eukaryotic translation initiation factor 4F (eIF4F), which is composed of eIF4E, eIF4G, and eIF4A. eIF4E is the cap-binding subunit, eIF4A is an RNA helicase, and eIF4G is a...

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Hlavní autoři: Yanagiya, Akiko, Svitkin, Yuri V., Shibata, Shoichiro, Mikami, Satoshi, Imataka, Hiroaki, Sonenberg, Nahum
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648241/
https://ncbi.nlm.nih.gov/pubmed/19114555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01187-08
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