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Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap

Eukaryotic mRNAs possess a 5′-terminal cap structure (cap), m(7)GpppN, which facilitates ribosome binding. The cap is bound by eukaryotic translation initiation factor 4F (eIF4F), which is composed of eIF4E, eIF4G, and eIF4A. eIF4E is the cap-binding subunit, eIF4A is an RNA helicase, and eIF4G is a...

詳細記述

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書誌詳細
主要な著者: Yanagiya, Akiko, Svitkin, Yuri V., Shibata, Shoichiro, Mikami, Satoshi, Imataka, Hiroaki, Sonenberg, Nahum
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648241/
https://ncbi.nlm.nih.gov/pubmed/19114555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01187-08
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