Modulation of the Conductance-Voltage Relationship of the BK(Ca) Channel by Mutations at the Putative Flexible Interface between Two RCK Domains

Calcium-dependent gating of the large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel is conferred by the large cytosolic carboxyl terminus containing two domains of the regulator of K(+) conductance (RCK) and the high-affinity Ca(2+)-binding site (the Ca(2+)-bowl). In our previous study, we loca...

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Detalhes bibliográficos
Main Authors: Kim, Hyun-Ju, Lim, Hyun-Ho, Rho, Seong-Hwan, Bao, Lin, Lee, Ju-Ho, Cox, Daniel H., Kim, Do Han, Park, Chul-Seung
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Channels, Receptors, and Electrical Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2157237/
https://ncbi.nlm.nih.gov/pubmed/17890381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108738
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