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The Intrinsic Flexibility of the Kv Voltage Sensor and Its Implications for Channel Gating

Analysis of the crystal structures of the intact voltage-sensitive potassium channel KvAP (from Aeropyrum pernix) and Kv1.2 (from rat brain), along with the isolated voltage sensor (VS) domain from KvAP, raises the question of the exact nature of the voltage-sensing conformational change that trigge...

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Detalhes bibliográficos
Main Authors: Sands, Zara A., Grottesi, Alessandro, Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367311/
https://ncbi.nlm.nih.gov/pubmed/16326912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072199
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