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Effects of Stable Suppression of Group VIA Phospholipase A(2) Expression on Phospholipid Content and Composition, Insulin Secretion, and Proliferation of INS-1 Insulinoma Cells

Studies involving pharmacologic inhibition or transient reduction of Group VIA phospholipase A(2) (iPLA(2)β) expression have suggested that it is a housekeeping enzyme that regulates cell 2-lysophosphatidylcholine (LPC) levels, rates of arachidonate incorporation into phospholipids, and degradation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bao, Shunzhong, Bohrer, Alan, Ramanadham, Sasanka, Jin, Wu, Zhang, Sheng, Turk, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156593/
https://ncbi.nlm.nih.gov/pubmed/16286468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509105200
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