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Isolation and analysis of inhibitors of transposon Tn3 site-specific recombination.
We have constructed a genetic bioassay for inhibitors of site-specific recombination by transposon Tn3 resolvase. Of 6,000 compounds tested, 26 inhibited in vivo, and 5 of these 26 inhibited in vitro. At least two inhibitors also inhibit the topoisomerase of resolvase. We have also identified analog...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1984
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC215648/ https://ncbi.nlm.nih.gov/pubmed/6330043 |
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